Design, Fabrication and Optimisation of Microneedles and Applicators for bio Fluid Sampling.
||23 October 2020
||1:00 PM - 2:30 PM
||For more information, please contact the Graduate Research School.
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Minimally invasive and painless microneedles (MN) patches have gained reputation for both drug delivery and sampling purposes. Material selection for biocompatibility and biodegradability, along with MNs fabrication process, play an important role in the final mechanical strength. Failure analysis, including buckling, fracture analysis, and reduction of insertion force is required for a pain-free and safe application. For sampling purposes, providing a condition for maximizing interstitial fluid (ISF) collections is the main challenge. Using lab experiments and simulations, this research aims to optimise MN materials, fabrication process and reduce insertion forces. It also tests and introduces techniques to maximise the volume sampling intake that will lead to design and manufacture of an applicator prototype for MN sampling purposes.